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Protein Scientist (Bioconjugation)

Job Title: Protein Scientist (Bioconjugation)
Contract Type: Permanent
Location: Cambridge, England
Industry:
Salary: Well paid
Start Date: 2019-07-21
Reference: BH-112341
Contact Name: Charles Leach
Contact Email: Charles.Leach@nesgt.com
Job Published: July 22, 2019 11:31

Job Description

Protein Scientist (Bioconjugation) – Cambridge – Permanent

Antibodies and their downstream therapeutic purposes are strong front runners in the ongoing fight in cancer research. My client, a leading Biotechnology company in the Cambridge region is currently seeking the expertise of a Protein Scientist (Bioconjugation) to advance their internal research programmes and contribute to client based projects around immune-peptidomics.

Protein Scientist (Bioconjugation) Key Responsibilities
:
  • Perform laboratory bioconjugation experiments to support internal programmes and client-based projects
  • Conjugate therapeutic small molecules and polymers to antibodies and proteins using a range of linker chemistries
  • Purification of antibody and protein conjugates by column chromatography (e.g. HIC, SEC, IEX) using automated systems (AKTA) and membrane ultrafiltration (TFF)
  • Further characterise proteins using analytical chromatography techniques, UV-Vis spectrophotometry, microfluidics and LC-MS
  • Contribute to antibody and protein conjugates developability assessment through assisting ex vivo serum stability and formulation development studies
  • Prepare presentations and present results at internal meetings and client meetings, contributing to writing of client reports.
Protein Scientist (Bioconjugation) Key Requirements:
  • PhD in relevant, Protein Biochemical discipline or BSc/MSc with accompanied 2-3 years+ industry experience.
  • Excellent, relevant technical skill set, particularly using protein purification, characterisation and linker technologies.
  • Knowledge or experience of synthetic organic chemistry.
  • Ability to work to a fast pace whilst maintaining a high standard of scientific rigor.
  • Excellent communication skills, integrating into a team with multiple varied projects. Confidence when updating clients on the milestones of their projects.
  • Good understanding of the research environment in the Biotechnology industry.
This permanent opportunity as a Protein Scientist (Bioconjugation) is a fantastic opportunity for somebody wishing to further their career with an award winning company and develop crucial interpersonal skills in a client focused research environment.